E3 Patient Safety Grant Program

Over the past eight years, the Cardinal Health Foundation has invested just under $8 million with 284 grants to hospitals, health systems or other health-related organizations.


Thank you for your interest in the Cardinal Health Foundation’s E3 – Effectiveness, Efficiency and Excellence in Healthcare Grant Program.

Cardinal Health develops and supports programs that help healthcare providers implement best practices that can truly transform patient care. Over the past eight years, the Foundation has invested just under $8 million with 284 grants to hospitals, health systems or other health-related organizations.  These projects have produced some very significant outcomes and insights.

We believe patient safety continues to be an issue of significance — however, we are modifying this program to take into account our rapidly changing demographics, the importance of the patient and the family as key partners in care and a renewed appreciation for the value medications, when used appropriately, can play in positive patient outcomes.  In addition, our experiences have shown us networks have the potential to further escalate the rate and spread of change – outcomes we are very interested in supporting.

In 2016, we sought proposals that included some or all of the following criteria:

  • Medication safety continues to be an area of focus, especially at transitions across the continuum of care from the hospital to home/to ambulatory settings.
  • Taking successful work to scale
  • Engaging patients and their caregivers/families
  • Publishing or otherwise sharing outcomes
  • Finding innovative and sustainable ways to effect long-term change 

Thank you to everyone who applied for the 2016 E3 Patient Safety Grant program; the application is now closed. We received many great proposals and are excited about implementing strategies that lead to positive patient outcomes.  Stay tuned for a list of the awarded grantees.

The 2017 Request for Proposal will be available by mid-September 2016.

E3 Patient Safety Grants resources

Who we are, What we do
Case Studies

Adding pharmacy services to a multi-disciplinary discharge team (PDF)
Franciscan Alliance Foundation on behalf of Franciscan St. Margaret Health-Hammond, Mishawaka, IN

Improving outcomes for high-risk chronically ill patients (PDF)
Trinity Medical Center, Rock Island, IL
Trinitas Regional Medical Center, Elizabeth, NJ

Improving transitions to home for post-acute seniors (PDF)
Senior Independence, Toledo, OH
Senior Services of Southeastern Virginia, Norfolk, VA
Southwestern Indiana Regional Council on Aging, Inc. Evansville, IN

Increasing access for the under-insured and uninsured (PDF)
West Virginia Health Right, Charleston, WV

Increasing medication safety for older adults (PDF)
Knute Nelson Foundation, Alexandria, MN

Increasing medication safety for patients admitted from the ER (PDF)
Trinity Medical Center, Rock Island, IL

Using the WHO Surgical Safety Checklist (PDF)
NorthShore University Health System, Evanston, IL
Virginia Mason Medical Center, Seattle, WA

Learn more

E3 Grant Frequently Asked Questions

43KB – PDF

2015 Recipients of E3 Patient Safety Grants

43KB – PDF