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GRIP™ Sealant

The GRIP™ sealant securely adheres to the surface of the vessel and dissolves within 30 days leaving nothing permanently behind. MYNX® devices use a soft, bio-absorbable, sponge-like sealant that absorbs blood and other fluids to seal the arteriotomy unlike some of the other vascular closure devices that use hard plastic, metal, or animal-based implants.

Product Description

The GRIP™ sealant consists of Polyethylene Glycol (PEG), which is non-thrombogenic and biocompatible, and it is found in a wide range of cosmetic and medical products including skin creams, cosmetics, toothpaste, eye drops, laxatives, and gel caps. It is an effective material to cover an incision and stop bleeding because of its biocompatibility and its ability to absorb blood quickly. The dual-action GRIP™ sealant adheres to the outside of the artery by interlocking with the vessel wall, instantly absorbing blood and fluids and expanding three to four times its original size. The MYNX® devices place the GRIP™ sealant without tugging, pulling, and cinching, and it dissolves within 30 days leaving nothing permanently behind.

Refer to the IFU for detailed procedure steps.

Clinical Articles

Mynx Vascular Closure Device Achieves Reliable Closure and Hemostasis of Percutaneous Transfemoral Venous Access in a Porcine Vascular Model
S. Sanjay Srivatsa, MBBChir1; Arjun Srivatsa1; Taylor A. Spangler, DVM, DACVP2. The Journal of Invasive Cardiology. February 2015

The MYNX ACE® Vascular Closure Device
Rajesh M. Dave, MD. Endovascular Today. February 2015

The MYNXGRIP® Vascular Closure Device
Hoang Minh Thai, MD, FACC, FSCAI, and Barry S. Weinstock, MD. Endovascular Today. April 2012.

Successful Reduction of Surgeries Secondary to Arterial Access Site Complications
A Retrospective Review at a Single-Center with an Extravascular Closure Device.
Noor S, Meyers S, Curl R. Vascular and Endovascular Surgery. May 2010;44(5):345-9.

A Prospective Randomized Single-blind trial of Patient Comfort Following Vessel Closure
Extravascular Synthetic Sealant Closure Provides Less Pain than a Self-tightening Suture Vascular Compression Device.
Fargen KM, Hoh BL, Mocco J. J Neurointerv Surg. 2011;3(3):219-23

Mynx Vascular Closure Device Early Ambulation Study
Vikranth R. Gongidi, DO; Ahsan Jafir, DO; and Vijay Verma, MD, FACC, FSCAI. Endovascular Today. October 2013

Occurrence of angiographic femoral artery complications after vascular closure with Mynx and AngioSeal
Fargen KM, Velat GJ, Lawson MF, et al. Journal of Neurolnterventional Surgery. 2013;5(2):161-4

Use of Vascular Closure Device After Access of Common Femoral Artery Through an Existing Stent
George JC. Vascular Disease Management. 2012;9(5):E68-E70.

Two Years of Extravascular Closure With the Mynx® Vascular Closure Device
The Baptist Memorial Hospital experience revisited.
David Wolford, MD, FACC. Endovascular Today. August 2010.

Mynx Closure in a Patient Treated for Chronic Total Occlusion of the Iliac Artery with Multiple Sheath Exchanges.
A Case Review. Michael S. Fenster, MD. TCTMD. May 2009.

About Vascular Closure

Vascular disease is a medical term given to the narrowing of blood vessels (arteries and veins). This type of disease occurs mostly in the heart, neck, and legs and if not caught or treated early, can cause serious health problems.

Regardless of where the narrowing occurs, diagnosis is crucial. To do so, the doctor makes a small puncture in either the femoral artery, near your groin area, or in the radial artery, near your wrist. A small hollow tube, called a sheath, is placed through the puncture site to allow your doctor access to your arteries, to visualize and, if necessary, treat the diseased vessel.

At the end of the procedure, the sheath is removed and a small hole, called an arteriotomy, remains in your artery. There are several methods and products designed to close the hole, including manual compression, sandbags, c-clamps, and a group of products called vascular closure devices.

Potentially Uncomfortable Manual Pressure
Until the early 1990’s, the standard method for closing the femoral artery at the groin after an interventional procedure was to apply manual pressure on the groin until the bleeding stopped. This process, which is still used today, can be uncomfortable for patients and requires a nurse or other clinician to apply manual compression to the area for 15-30 minutes. This is often followed by placement of a compression bandage on the groin while the patient lies flat on his or her back for 6-8 hours, which many patients describe as the most uncomfortable part of the procedure.

Vascular Closure Doesn’t Have to be a Pain
Compared to manual compression, vascular closure devices close the access site faster and help patient comfort by allowing the patient to get out of bed and be discharged from the hospital sooner. Cardinal Health has advanced vascular closure device options with the MYNX® product family of vascular closure devices, which are designed to provide gentle and safe closure without cinching, tugging or potentially uncomfortable manual compression.