2008 Cardinal Health Patient Safety Grant Recipients >
Wayne State University, Children's Hospital of Michigan
Utility of End Tidal Carbon Dioxide Monitoring in Detection of Hypoxia During Sedation for MRI Brain in Children with Developmental Disabilities
Team members
From left to right:
- Lana Goryaynova, Registration; Jeannie Zoubi, Sedation nurse; Christina Karcher, Sedation nurse; Dr. Rivera, Sedation physician; Dr. Nirupama Kannikeswaran; Dr. Sethuraman, Co-investigator; Nancy Kragl, Sedation nurse; Rose Emling, Sedation nurse
In our pilot study, we found that children with developmental disabilities have a three times greater incidence of hypoxia during sedation for brain MRI in when compared with normal children. Previous studies in developmentally normal children have shown that changes in exhaled carbon dixoide occur on an average at least 5 minutes prior to hypoxia. We plan to study the utility of continuous monitoring of exhaled carbon dixoide (ETCO
2) in the detection of hypoxia during sedation for MRI brain in children with developmental disabilities. We will be measuring and describe changes in ETCO2 associated with different sedatives in children with developmental disabilities undergoing MRI brain and studying the effectiveness of continuous ETCO
2 monitoring in earlier recognition of hypoxia thereby reducing it’s incidence in children with developmental disabilities who undergo MRI brain.
Program inquiries
Dr. Nirupama Kannikeswaran
Phone: 313.745.5260
Wayne State University, Children's Hospital of Michigan
3901 Beaubien Blvd
Detroit, MI 48201