The Caprini model relies on several sets of risk factors, each with weighted point values. Together these values result in a cumulative score. This score determines the recommendations for prophylaxis.
Research supports the use of this model. A retrospective analysis of 1,078 knee and hip replacement patients described in Clinical and Applied Thrombosis/Hemostasis found that the Caprini model stratified patients with much greater accuracy than the orthopedic departmental protocol. Caprini identified seven out of eight patients who experienced VTEs as high risk.
However, Caprini, like other individualized point scoring systems, has a significant drawback —its complexity. A review of studies in Journal of Thrombosis and Thrombolysis notes that hurried clinicians may not complete the assessment correctly, and integrating its scoring system into order sets can be challenging.
For hospitals without sophisticated clinical decision support infrastructure, a simpler model may be a better choice, according to review published in the Journal of Hospital Medicine.