Compliance with USP <800> and associated standards might feel overwhelming as facilities decide how to update and improve upon current standard operating procedures. However, organizations affected by USP <800> can develop a compliance roadmap by following these steps:
1. Read the USP <800> standard at www.usp.org.
2. Audit current use of hazardous drugs and perform an assessment of risk. Compliance starts with an audit and assessment of risk, since it is based on what you do with what you have. One way to conduct an audit is by following the hazardous drug workflow. This begins with selecting hazardous drugs and includes storing, followed by ordering, dispensing, administering and monitoring them.
This helps to identify the exposure risks and create a plan to minimize them, which could include efforts to determine when a staff member should wear chemotherapy-rated gloves, provide separate storage spaces for drugs, and deliver new training to encourage adoption and of safe handling best practices.
3. Apply the Hierarchy of Controls published by NIOSH (below) to help manage risks. This hierarchy looks at possible controls from most to least effective.