The addition of IPC to pharmacological prophylaxis may result in further reduction of VTE.
A meta-analysis of studies (11 studies, 7431 patients) evaluating the efficacy of adding IPC to pharmacological prophylaxis in high risk patients* demonstrated a significant reduction in deep vein thrombosis (DVT) versus pharmacological prophylaxis alone. (P<0.05)3
*"The studies included in this review were carried out in a wide range of patient groups undergoing mainly orthopedic but also urological, cardiothoracic, general surgery, and gynecology procedures. Most of the patients had a high-risk procedure or condition and, therefore, the results of this review are not necessarily applicable to different patient groups, including neurosurgical and trauma patients."3